--------------------------------------------------------------------- X-RAY VISION: THE LARGE-SCALE DISTRIBUTION AND EVOLUTION OF GALAXY CLUSTERS Clusters of galaxies are prime tracers of the distribution and evolution of matter on the largest scales. Large, statistically well-defined cluster samples are needed for such studies but are hard to compile at optical wavelengths because of severe systematic biases that are difficult to quantify and thus often uncorrectable. I will present an overview of recent attempts aimed at overcoming the limitations of optical cluster searches by using X-ray selection. Specifically I will discuss and present results from three projects: - the first systematic X-ray search for clusters of galaxies behind the plane of the Milky Way that will allow us to identify and account for the largest concentrations of mass affecting large scale flows in this optically obscured part of the local universe, - an X-ray search for distant (z>0.8) clusters of galaxies that attempts to constrain cluster evolution at the highest redshifts and recently discovered the most massive galaxy cluster at z~0.9 currently known, - a near-all-sky X-ray cluster survey that has already discovered ten times more very massive and distant clusters than any previous X-ray or optical survey, and that will allow us to probe with unprecedented accuracy the physical and cosmological framework of cluster formation. ---------------------------------------------------------------------