Observations of Interstellar Molecules with a Novel Infrared Spectrograph John Lacy University of Texas, Austin Infrared observations have provided important information about interstellar and protostellar molecules, but are hampered by limited resolution and sensitivity. To extend our capabilities in the mid-infrared, we have constructed a cross-dispersed echelle spectrograph, TEXES, capable of 3 km/s resolution. In the two years TEXES has been in use of the IRTF, we have studied molecules in various astrophysical environments. I will talk about our observations of the Kleinmann-Low region in Orion, where emission and absorption lines of several molecules are helping us to understand the complex structure of the nearest high-mass star forming region