Title: First Science Results from GOODS Bahram Mobasher Space Telescope Science Institute Abstract: I present a brief overview of the Great Observatories Origins Deep Survey (GOODS). Using the final data products from the multi-waveband observations with HST/ACS and ground-based ancillary data, I will discuss the very first scientific analysis of the GOODS/ACS observations. The exquisite sensitivity, high spatial resolution and the large area covered by the GOODS - 0.1 sq. deg., 33 times larger than the two HDFs - has provided the best sample to date for various investigations. I will present a study of the ultraviolet luminosity density and the star formation density of Lyman Break Galaxies out to z~6 (less than 7% of the cosmic age). Using the wavelength coverage and high angular resolution of the GOODS, I will discuss the rest-frame morphology of star-forming galaxies and show evidence that a significant fraction of star formation activity is triggered by mergers/ interaction. Moreover, I will present results from the first study of the evolution of galaxy sizes in the range z~6 to z~1, and comparison with hierarchical model predictions concerning merging of smaller galaxies into the larger ones. Using photometric redshifts, I will present constraints on bulge formation in galaxies at 1 < z < 2. Finally, I will discuss the search results leading to discovery of 15 Type Ia SNe at z > 1, used to measure the SNe rates and their relation to star formation rate and to constrain cosmological parameters.